Mole Analyzer - Univ. of Tuebingen

This program was developed at the University of Tuebingen in Germany, based on the software program FotoFinder from TeachScreen Company, Griesbach, Germany. Its purpose is computed image analysis of pigmented moles surrounded by pale skin.

In a first step hairs, pieces of fluff, bubbles and etc. are digitally subtracted, and than the border of the lesion is determined by approximation from both sides (this step can be corrected manually). Subsequently, the area and other geometric parameters are measured and the border and its regularity and sharpness are determined. The features demonstrated in this program were selected from more than 100 parameters which can be used for distinguishing between different pigmented moles and which are examined as criteria to judge the dignity of pigmented moles.

There are two main aims of this computed image analysis program:

1. The image analyzer was programmed in order to detect changes in pigmented lesions during the follow-up of patients. With this program it is possible to detect minimal changes in the size of the lesion, in its pigmentation, in its structure and border. This aims on making the indications for excision of moles more secure.

2. The program likewise serves as utility to judge the dignity of the pigmented lesions. Several parameters are classified in scores when the 20fold magnification is used. The scores vary between one and eight and higher scores than 6 may indicate developing malignancy. However, there is not yet a clear cutoff-point for determining malignancy. The knowledge of an experienced physician is needed to finally interprete these images.